The effect of gap length on double-strand break repair in Drosophila.
نویسندگان
چکیده
When a double-strand break has a gap between the broken ends, the missing information can be restored through synthesis from a homologous template. Here we address the question of how long such a gap can be before this process fails. We measured the frequency of homologous repair in the Drosophila germ line following the creation of gaps of specific sizes ranging from 3.8 to 210 kb. We found that gaps of >11 kb.
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ورودعنوان ژورنال:
- Genetics
دوره 173 4 شماره
صفحات -
تاریخ انتشار 2006